KSOM Dept of PopPublicHS_1 lineWhtGold

COVID-19 Pandemic Research Center (CPRC)

SARS-CoV-2 Antibody Testing in Vulnerable Communities


Low-income residents of Los Angeles County are dying of COVID-19 at a rate nearly four times that of residents in wealthier communities. The current pandemic is magnifying existing health disparities and is creating an immediate need for increased testing, better understanding of personalized risk in low-income households, connection to health care and support services, and culturally-tailored information and recommendations. The primary goal of the study is to recruit a random sample of 2000 persons (500-1000 households) who have sought care at AltaMed Health Services (a Federally Qualified Health Center in Los Angeles), and test them for SARS-CoV-2 antibodies. A secondary objective is to integrate test results with a brief set of self-report measures on social determinants of health to predict risk of positive tests. Households are invited to complete a survey and members are offered $20 to participate in antibody testing. We will estimate the true proportion of positive tests and produce displays of the frequency distribution of positive tests as they relate to most common medical conditions and social determinants of health, caregiving responsibilities, and food access/distance needed to travel to obtain essential goods. This project will provide valuable information about those most at risk of contracting COVID-19 and will offer actionable information that may help prevent further spread of the disease.

Principal Investigator
Michael Hochman, MD, MPH
Associate Professor of Clinical Medicine Director of the Gehr Center for Health Systems Science and Innovation

Jason Doctor, PhD
Professor and Chair of Health Policy and Management, University of Southern California

Rajan Sonik, JD, PhD, MPH
AltaMed Health Services Corp.

Neeraj Sood, PhD
Price School of Policy, USC

Co-Director of SC CTSI and Project Partner
Michele Kipke, PhD
University of Southern California, Children’s Hospital Los Angeles

Research Program Manager
Mika Kadono, PhD, MPH, MA
AltaMed Health Services Corp.

Project Director
Tara Knight, PhD
University of Southern California

Project Manager
Alissa Maier, MPH
University of Southern California

Research Coordinator
Leslie Escobar
University of Southern California

Paolo Hernandez
University of Southern California